Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp365 | Other diseases of bone and mineral metabolism | ECTS2014

Alkaline phosphatase bone isoform B1x: a marker of impaired osteoblastic function in patients with renal osteodystrophy

Haarhaus Mathias , Marie-Claude Monier-Faugere , Magnusson Per , Malluche Hartmut

Renal osteodystrophy encompasses the bone histologic abnormalities seen in patients with chronic kidney disease (CKD). The bone-specific alkaline phosphatase (BALP) isoform B1x is exclusively found in serum of some CKD patients. The aim of this study was to examine the relationship between serum BALP isoforms and histologic abnormalities of bone in patients with CKD on chronic dialysis (CKD-5D).Anterior iliac crest bone samples from 40 CKD-5D patients we...